A suicide attack in eastern Afghanistan has killed at least 14 people, including three Americans - a day after the US death toll in the 11-year war reached 2,000.
The American Nato service members' translator, six civilians and four Afghan police were also killed and 37 wounded in the attack on a joint Nato-Afghan foot patrol through Khost city, Najeeb Danish.
The city's governor said in a statement: "Today at around 8:30 am a suicide bomber on a motorcycle targeted a joint patrol in Khost city in a crowded area.
"In this inhuman attack three police and 37 civilians were wounded, and six civilians and four police, including the commander of the quick reaction forces, were killed".
The deaths take coalition casualties to at least 347 this year. On Sunday, the number of American military personnel killed in the Afghan war reached 2,000 following an insurgent attack.
The death toll in Afghanistan has climbed steadily in recent months with a spate of attacks by Afghan army and police against American and Nato troops.
The latest blast comes a day after Nato announced that a firefight between coalition troops and their Afghan allies killed an ISAF soldier, a civilian contractor and three Afghan army troops.
The incident was initially described as a suspected insider attack, but it was later suggested that either insurgent fire or a verbal argument between the troops sparked the shooting.
However Nato has said that insurgent attacks on its forces dropped by five percent in the first eight months of this year compared to 2011, though they're still running at around 100 a day.
It claims the decline in attacks demonstrates that its troops have been able to "reverse the momentum" of the insurgents' campaign, although the Taliban "strongly and categorically" deny the claim.
August was the second deadliest month in five years for civilians in Afghanistan, with a total of 374 killed and 581 injured.