The new boss of Trinity Mirror is to unveil a restructuring of the company that will involve the departure of the long-serving head of its regional newspapers arm.
Simon Fox, who took over the owner of the Daily Mirror last month, has decided to combine its national and regional publishing divisions.
Mark Hollinshead, who oversees national titles including the Mirror and Sunday People, will head the business and join Trinity's board.
Georgina Harvey, managing director of Trinity's regionals arm since 2005, is expected to leave as part of the shake-up.
Ms Harvey is one of the newspaper industry's most senior women executives, and has been president of the Newspaper Society since 2010.
Her likely departure would mean that Trinity has lost its three highest-ranking women this year, following the exits of Sly Bailey, Mr Fox's predecessor, and Tina Weaver, former editor of the Sunday Mirror.
People close to Trinity said on Saturday that the restructuring had not yet been finalised and that it was possible that Ms Harvey could remain at the company in another role.
The reorganisation is designed to improve the operational efficiency of Trinity at a time when it continues to face intense pressure from declining circulations and advertising revenues.
Earlier this year, Trinity axed the editorships of the Daily and Sunday Mirror titles, installing the editor of the People to oversee the national newspapers.
Mr Fox was a surprise choice to head the company, with analysts questioning his lack of newspaper industry experience.
His time as chief executive of HMV, the struggling high street retailer, was nevertheless viewed by Trinity's chairman, David Grigson, as a useful grounding in sectors where traditional revenue streams are being eroded by the internet.
Ms Bailey had become a focus for investor anger over her pay packages during a period of poor share price performance.
Trinity owns many of Britain's leading regional newspapers, publishing more than 130 daily and weekly titles and offering more than 500 digital products.
Among its portfolio are the Liverpool Echo, Manchester Evening News, Birmingham Post and six Metro titles in cities including Cardiff and Newcastle.
Trinity declined to comment.
