Arsene Wenger will oversee a third FA Cup Final in four years after Alexis Sanchez secured a dramatic extra-time winner to beat Manchester City 2-1 in Sunday's semi-final.
The victory has added gloss to a season which has proved tough for both Wenger and the club, though Arsenal's immediate focus must be on securing Champions League qualification.
The Gunners sit seven points off the top four with a game in hand, and a win against title holders Leicester could prove invaluable with fellow top-four hopefuls Manchester City and Manchester United facing off on Thursday night.
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Arsenal host Leicester at Emirates Stadium with kick-off scheduled for 7:45pm on Wednesday, April 26.
TV AND LIVE ONLINE COVERAGE
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Arsene Wenger will consider whether to stick with the three-man defence which helped Arsenal record wins against Middlesbrough and Man City.
Gabriel, Laurent Koscielny and Rob Holding have formed a good understanding at the back, with Alex Oxlade-Chamberlain currently keeping Hector Bellerin out of the team at right wing-back.
But Bellerin may well return along with the likes of Theo Walcott given Arsenal's gruelling extra-time win at Wembley, with Danny Welbeck likely to start given his impressive cameo off the bench after Olivier Giroud's struggles.
David Ospina, Shkodran Mustafi, Lucas Perez and Jeff Reine-Adelaide are all currently sidelined.
Leicester are not completely safe from relegation, though have two games in hand on their most realistic rivals for the drop.
Craig Shakespeare also no longer has to juggle his squad after Atletico Madrid knocked the Foxes out of the Champions League quarter-finals, with Claudio Ranieri's replacement expected to name his strongest possible XI at the Emirates.
Islam Slimani will miss out with a groin strain, while captain Wes Morgan is out with a hamstring complaint.
Papy Mendy has undergone ankle surgery, and is out for the rest of the season.
Arsenal starting XI: Cech; Gabriel, Koscielny, Holding; Bellerin, Xhaka, Elneny, Monreal; Sanchez, Ozil; Welbeck
Leicester starting XI: Schmeichel, Simpson, Benalouane, Huth, Fuchs, Mahrez, Ndidi, Drinkwater, Albrighton, Okazaki, Vardy
BETTING ODDS (via 888 Sport)
- Arsenal to win: 10/17
- Leicester to win: 22/5
- Draw: 17/5
Click here to place a bet. Odds correct as of April 24 at 2pm.