Even though the outcome of Sunday’s game is not expected to have a direct bearing on Wenger’s future another defeat to a top six rival after last week’s 2-0 loss at Tottenham would see the pressure ratchet up on the Frenchman even further.
That defeat at White Hart Lane has not entirely ended Arsenal’s challenge for a top four spot, going into the weekend they sit six points behind fourth-placed Manchester City with a game in hand.
But failure to beat a United side dogged by a string of injuries to key players, particularly in defence, would surely mean the end to Arsenal’s 20 year record of Champions League qualification. And Wenger has never bested Mourinho in the Premier League.
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Arsenal host Manchester United at the Emirates Stadium, with kick-off at 4pm on Sunday May 7.
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Arsenal are not believed to have suffered any new injuries from their bruising 2-0 defeat at White Hart Lane but are unlikely to see their squad swelled by the return of German centre-back Shkodran Mustafi, who is also expected to miss the visit to Southampton with a thigh injury, and is a doubt for the following game at Stoke.
Santi Cazorla remains a long-term absentee whilst David Ospina and Lucas Perez, both players whose long-term future at the Emirates is surrounded in doubt, continue to find themselves on the sidelines.
Wenger is expected to continue with the 3-4-2-1 he has deployed in his last four games despite finding his side outclassed at White Hart Lane in a system that they continue to struggle with.
Manchester United’s injury woes have been so severe that Mourinho joked after the draw with Swansea that his players “could walk to the toilet and break a leg” after he saw Luke Shaw and Eric Bailly depart through injury.
They joined Marcos Rojo, Chris Smalling, Timothy Fosu-Mensah and Phil Jones on the sidelines and Mourinho’s men still have the matter of a Europa League semi-final to get through unscathed.
Zlatan Ibrahimovic is also out with the anterior cruciate ligament injury to his knee that could mean he has played his last game for United. Record signing Paul Pogba is expected to be available though.
Arsenal XI: Cech; Gabriel, Koscielny, Monreal; Oxlade-Chamberlain, Xhaka, Ramsey, Gibbs; Ozil, Sanchez; Giroud
Manchester United XI: De Gea; Valencia, Tuanzebe, Blind, Darmian; Carrick, Herrera, Pogba; Mkhitaryan, Rashford, Martial
BETTING ODDS (via 888 Sport)
Arsenal to win: 19/20
Manchester United to win: 14/5
All odds correct as of 16:45 on Monday May 1.