The midfielder has been sidelined since pulling up during the warm-up of the loss to Villarreal, but is back among the substitutes this week.
Elsewhere, David Luiz is Mikel Arteta's only other fitness concern and there is hope he will make one last appearance for the Gunners before the end of the season with his impending summer exit confirmed - though he misses out here.
Arteta beat Chelsea last week but have switched things up for another London derby.
Bukayo Saka struggled in a wing-back role at Stamford Bridge and has been deployed further forward here.
Emile Smith Rowe and Nicolas Pepe complete the three behind lone striker Pierre-Emerick Aubameyang.
Arsenal XI: Leno, Chambers, Holding, Gabriel, Tierney, Elneny, Partey, Pepe, Smith-Rowe, Saka, Aubameyang
Subs: Ceballos, Lacazette, Odegaard, Willian, Cedric, Pablo Mari, Ryan, Xhaka, Martinelli
Arsenal provisional squad: Leno, Ryan, Bellerin, Cedric, Chambers, Gabriel, Mari, Holding, Tierney, Xhaka, Elneny, Ceballos, Partey, Saka, Odegaard, Smith Rowe, Willian, Pepe, Aubameyang, Martinelli, Lacazette, Nketiah, Balogun.