Barcelona pair Frenkie de Jong and Memphis Depay are facing a spell on the sidelines after returning from international duty with the Netherlands carrying injuries.
De Jong left the field at half-time during last week's Nations League win over Poland, while Depay hobbled off later in the same game.
Neither player featured in Sunday's win against Belgium after being given permission to return to club side Barcelona early.
Barca confirmed on their official website on Monday that both players remain injured and are not being considered for selection against Real Mallorca next weekend.
Reports from Spain suggest De Jong could return within a week, but Depay is facing closer to a month out of action with an injury to his left thigh.
The news comes on the same day that Barca announced Ronald Araujo is to undergo thigh surgery on Wednesday, ruling the defender out for the remainder of the year.
Fellow centre-back Jules Kounde also suffered an injury on international duty with France and is expected to miss a month.