Former business secretary Sir Vince Cable has confirmed he will be trying to win back his former seat of Twickenham.
Following the PM's call for a snap General Election, he wrote on Twitter: "I plan to lead fight back to recapture Twickenham for Lib Dems. Brexit. Heathrow. School cuts. Social care. Plenty to campaign on."
The 73-year-old held the south-west London seat from 1997 to 2016, and must overcome a slim Conservative majority of 2,017 votes.
Sir Vince will be hoping to replicate the success of the Richmond Park by-election in 2016, where Lib Dem MP Sarah Olney decisively beat Zac Goldsmith after running an anti-Brexit campaign.
Declaring his intention to stand with the phrase, "Bring it on!" he said he was "surprised" Mrs May had gone back on her pledge not to call a general election until 2020.
The strong local opposition to a hard Brexit in Twickenham, which had a Remain vote of around 70%, makes the seat one of the best hopes for the party.
Sir Vince said he would also be campaigning on topics like Heathrow expansion, social care and cuts to local schools.
Fellow Lib Dems Sir Simon Hughes, Sir Ed Davey and ex-Cambridge MP Julian Huppert have also been re-selected to fight seats they lost at the last election.
Meanwhile, former Labour home secretary MP Alan Johnson - who has represented Hull West and Hessle for 20 years - has decided he will not stand for re-election in his seat.
The veteran Labour MP announced his decision in a letter to his constituency party.
He wrote: "Every day has been a privilege and a pleasure but it can't go on for ever."
Referencing " the anguish of a mid-term by-election" he said his "personal decision is whether to retire now or in 2022 when I'll be into my 70s".
He concluded: "I've decided that going now will give me the opportunity to do other things with my life and is therefore in the best interests of me and my family. I also think it's best for the party."
Staunch Corbyn critic Tom Blenkinsop, Labour MP for Middlesbrough South and East Cleveland, also announced he would not be standing for re-election, citing "irreconcilable differences" with the party leadership.