Lukaku came off the bench to inspire the win at Villa Park and could make his first start in three weeks against Brighton.
After Liverpool lost 1-0 at Leicester, Chelsea have a chance to move three points ahead of Jurgen Klopp’s side ahead of their meeting with them at Stamford Bridge on Sunday.
Brighton go into the game off the back of their first win in 12 Premier League matches after goals from Leandro Trossard and Neal Maupay gave them a 2-0 win over Brentford on Boxing Day.
Date, kick-off time and venue
Chelsea vs Brighton is scheduled for a 7.30pm GMT kick-off on Wednesday, December 29, 2021.
Stamford Bridge in west London will host the game.
Where to watch Chelsea vs Brighton
TV channel: The match is exclusively available on Amazon Prime Video.
Live stream: Amazon Prime subscribers will be able to watch the match online via the Amazon Prime Video website or app.
Live blog: Keep up to date with all the action on Standard Sport’s live blog.
Chelsea vs Brighton lineups and team news
Chelsea XI: Mendy, Azpilicueta, Christensen, Rudiger, James, Kovacic, Jorginho, Hudson-Odoi, Mount, Pulisic, Lukaku
Subs: Arrizabalaga, Alonso, Kante, Chalobah, Saul, Barkley, Ziyech, Havertz, Sarr
Brighton XI: Sanchez, Lamptey, Veltman, Burn, Cucurella, Bissouma, Lallana, March, Moder, Mac Allister, Maupay
Subs: Webster, Mwepu, Gross, Alzate, Welbeck, Steele, Duffy, Richards, Ferguson
Chelsea vs Brighton prediction
Brighton have been hard to beat despite their lack of wins, and Chelsea are struggling at home, but the return of Lukaku should help them get over the line in this one.
Chelsea to win, 2-0.
Head to head (h2h) history and results
Brighton won their first meeting in 1933, but have failed to beat Chelsea since.
Chelsea wins: 12
Brighton wins: 1