A young Spurs squad began the Nuno Espirito Santo era against Leyton Orient on Saturday, with teenage forward Dane Scarlett notching in a hard-fought 1-1 friendly draw.
It’s more fourth-tier opposition in store for Tottenham in midweek, with the game being played against a backdrop of fervent transfer speculation as the likes of Pierluigi Gollini, Bryan Gil and Cristian Romero are all heavily linked with moves to N17.
The visitors will remain without their Euro 2020 stars such as England captain Harry Kane at the Colchester Community Stadium.
Hayden Mullins’ hosts, meanwhile, head into Wednesday’s match on the back of two 60-minute defeats at newly-promoted Watford and a 3-0 win over non-league Billericay Town.
Where to watch Colchester vs Tottenham
TV channel: The match is not being televised live in the UK.
Live stream: However, the match will be available to watch online for free via Spurs TV on the official Tottenham website.