After favourable weekend results that included each of Chelsea, Manchester United and Liverpool dropping points, Graham Potter’s side travel to Selhurst Park knowing a win would take them top after an impressive start to the season.
They meet a Palace side that will relish the comforts of home after an impressive performance against Tottenham Hotspur two weekends ago.
Patrick Vieira could give Odsonne Edouard a start as his striker, while Potter will be worried about Yves Bissouma after his knee knock, though the influential midfielder has trained ahead of the fixture.
He may have a key role to play in disrupting impressive Chelsea loanee Conor Gallagher in what is likely to be a fiercely-fought clash.
Date, kick-off time and venue
Crystal Palace vs Brighton is scheduled for an 8pm BST kick-off tonight at Selhurst Park
Where to watch Crystal Palace vs Brighton
TV channel: The match will be televised on Sky Sports Premier League and Main Event, with coverage starting at 7pm.
Live stream: Sky Sports subscribers will be able to watch the match online via Sky Go
Crystal Palace vs Brighton lineups and team news
Crystal Palace XI: Guaita, Ward, Andersen, Milivojevic, Mitchell, Gallagher, Guehi, McArthur, Ayew, Edouard, Zaha
Subs: Butland, Olise, Kouyate, Hughes, Mateta, Schlupp, Clyne, Benteke, Kelly
Brighton XI: Sanchez, Duffy, Dunk, Burn, Veltman, Gross, Lallana, Cucurella, Trossard, Welbeck, Maupay
Subs: Lamptey, Connolly, Mac Allister, Moder, Alzate, March, Steele, Roberts, Richards
Crystal Palace vs Brighton prediction
In a game likely to be full of spice and spite, perhaps both on and off the pitch, this one could be tight. Brighton have looked very, very good so far this season but Palace have shown promise, too, and will relish a derby encounter under the lights at Selhurst Park.
Crystal Palace 1-1 Brighton
Head to head (h2h) history and results
Crystal Palace wins: 40
Brighton wins: 40
Betting odds and tips
Crystal Palace to win: 2/1
Brighton to win: 13/8
Odds via Betfair (subject to change). Click here to find out more.