Winger Eze suffered a serious Achilles injury in training this week and looks set for months on the sidelines.
Tyrick Mitchell contines at left-back after scoring his first Palace goal in the win against Villa, meanwhile.
Hodgson has also decided to recall Vicente Guaita in goal after Jack Butland started at the weekend.
Scott Dann misses out along with the likes of captain Luka Milivojevic, Connor Wickham, Nathan Ferguson and Mamadou Sakho, but Nathaniel Clyne and Patrick van Aanholt are on the bench alongside teenage forward Jesurun Rak-Sakyi.
Crystal Palace XI: Guaita, Ward, Tomkins, Cahill, Mitchell, Kouyate, McCarthy, Schlupp, Townsend, Benteke, Zaha
Subs: Butland, Van Aanholt, Ayew, Mateta, Clyne, Batshuayi, Kelly, Rak-Sakyi, Riedewald