With Dubois's British title, Joyce's Commonwealth crown and the vacant European belt at stake, the younger Dubois was forced to take a knee early in the 10th and failed to answer the referee's count.
Dubois was unable to see out of his left eye by the end of the fight after it was repeatedly targeted, but vowed to return stronger from the loss.
"What can I say, he caught me with a good jab," Dubois told BT Sport. "I couldn’t see out of the eye. I can’t explain.
"I was trying my best and this happened. I’m a tough guy, I’ll come again for sure."
. @TheAthleticUK understands that Daniel Dubois suffered a broken orbital socket and nerve damage to his left eye during last night’s fight against Joe Joyce. The fight ended in the 10th round after Dubois took a knee and failed to beat the count #DuboisJoyce pic.twitter.com/8z9FIWgkbs
— Sarah Shephard (@SarahShepSport) November 29, 2020
Joyce added: "I started looking at that eye, it was starting to swell and I was moving away from his right hand and trying to stay off the ropes."
The Athletic report that Dubois was taken to Moorfields Eye Hospital after the fight where the extent of the injury was confirmed.