Hamilton held off Verstappen against the odds in Bahrain after his young title rival had dominated practice and qualifying, but the European venue is a different task.
The fast and flowing anti-clockwise layout is also narrower and bumpier than Bahrain, and with fewer opportunities to overtake which means track position and strategy will play a bigger part.
Red Bull's Verstappen has started the last two races -- Abu Dhabi at the end of last season and then Bahrain in March - on pole position and the 23-year-old will be looking to complete his hat-trick. It looks set to be another intriguing battle.
Here’s all the information you need to tune in...
When is the 2021 Emilia Romagna Grand Prix?
The 2021 Emilia Romagna Grand Prix is scheduled to take place on Sunday, April 18, 2021, with practice beginning on Friday.
What time is the 2021 Emilia Romagna Grand Prix?
On Sunday, the race itself is set to get underway at 2pm BST.
Qualifying starts slightly earlier than usual to avoid a clash with Prince Philip’s funeral, taking place from 1pm for an hour. A minute’s silence will be held beforehand.
Practice kicks off on Friday with FP1 from 10am BST and FP2 at 1.30pm BST. FP3 will start at 10am BST on Saturday, moving forwards an hour to accommodate the earlier qualifying.
How can I watch the 2021 Emilia Romagna Grand Prix?
TV channel: The race will be shown LIVE on Sky Sports Main Event and F1 channels. Coverage of FP1 starts at 9.30am BST on Friday with FP2 following at 1.15pm BST.
FP3 coverage is from 9.45am BST with qualifying from 12pm BST. The race coverage starts on Sunday at 12.30pm BST.
Live stream: Subscribers can stream the action LIVE via the SkyGo website and app.