The “Covid winter plan” is expected to place more areas into the higher tiers to keep the virus under control to ensure further restrictions are not needed, No 10 said.
And while some local measures will be the same as those in the previous system, some tiers will be strengthened to safeguard the gains made during the national lockdown.
The PM will accept that the measures are difficult but will make clear they are not to last longer than is absolutely necessary and will take into account the need to support the economy.
The cabinet is expected to discuss and sign off the plan on Sunday before Johnson announces it to parliament the following day when the full details are expected.
The plan will set out how people will be able to spend their Christmas, but ministers have made clear that the festive season will be different to normal, with some restrictions expected to remain in place.
Ministers will set out what tier each area will be placed into on Thursday and MPs are expected to be given the vote to approve the new tiering system, as promised by Johnson, in the days before it comes into force.
They are optimistic that restrictions can be gradually reduced in the run-up to spring, providing vaccines are approved by regulators, allowing a plan for the roll-out to begin next month before a wider programme in the new year.
But the PM will be wary of a rebellion from backbench Tory MPs who are opposed to new restrictions.
During a vote on the current four-week system earlier this month, 32 Conservatives rebelled to oppose the measures and 17 more, including former prime minister Theresa May, abstained.
Subsequently, a “Covid recovery group” led by former chief whip Mark Harper and ex-Brexit minister Steve Baker has formed to resist new measures, with suggestions 50 Tories have enlisted.
But Downing Street will hope an easing at Christmas, potential vaccines on the horizon and new scientific evidence will lessen the scale of a rebellion, with the government’s Scientific Advisory Group for Emergencies (Sage) expected to publish papers on Monday stating that the previous tiers were not strong enough.
Labour has so far been supportive of the need for restrictions to slow the spread of Covid-19, and a full-scale Commons defeat on the plan is unlikely.
A No 10 spokeswoman said: “Everyone’s efforts during the current national restrictions have helped bring the virus back under control, slowed its spread and eased pressures on the NHS.
“But the prime minister and his scientific advisers are clear the virus is still present – and without regional restrictions it could quickly run out of control again before vaccines and mass testing have had an effect.
“That would put in jeopardy the progress the country has made, and once again risk intolerable pressure on the NHS.”
This article originally appeared on HuffPost UK and has been updated.