The claim will undergo a series of checks to ensure its validity before the windfall is paid.
Camelot said no information will be released on whether the claimant is an individual or a syndicate winner, or where the ticket was purchased, unless the ticket-holder decides to go public.
Andy Carter, Camelot’s senior winners’ adviser at the National Lottery, said: “This is absolutely incredible news.”
The winning EuroMillions numbers from Tuesday’s draw were 06, 23, 27, 40, 41 – plus the Lucky Star numbers 02 and 12.
Mr Carter said: “Last night saw history made with the biggest-ever National Lottery prize won by a UK player, and we’re ecstatic that we’ve received a claim.
“Our focus is now on supporting the ticket-holder through the process and helping them start to enjoy their truly life-changing and record-breaking win.”
The holder will be able to buy 11 Boeing 747 jets, 23 Pisces-VI Submarines, Southampton Football Club or a townhouse in London’s Mayfair, complete with steam-room and plunge pool, cinema room and fully-equipped chef’s kitchen.
It also means they are richer than Adele (worth £150 million).