The pedestrian, a man in his late 20s was, taken to hospital in a critical condition. His family have been informed.
Two cars - thought to be an Audi and a Zip hire car - are believed to have been involved in the collision.
Both drivers failed to stop, and no arrests have yet been made.
Scotland Yard is appealing for witnesses and information about the incident.
Officers from the Met’s Roads and Transport Policing Command are investigating, and in particular, are asking anyone who has dashcam footage to come forward.
#FinsburyPark - the #A503 Seven Sisters Road is closed between Blackstock Road and Finsbury Park Station because of a serious collision. Bus routes 29, 253, 254, 259 and N279 are diverting pic.twitter.com/AQj0S05dAa
— BBC Radio London Travel (@BBCTravelAlert) January 16, 2023
Any witnesses or anyone with any information is asked to call police on 020 8246 9820 or 101 or contact via Twitter @MetCC. Please quote CAD501/16JAN
To give information anonymously contact Crimestoppers on 0800 555 111 or online at crimestoppers-uk.org.