A 15-year-old boy has been stabbed to death after a fight broke out close to a high school early on Friday.
The force were called to Blyth Road, Hayes close to Global Academy to reports of the fight at 8.30am.
Paramedics and the air ambulance were called but despite their efforts to revive him, the teenager died at the scene.
Police commander for Hillingdon, Chf Supt Peter Gardner, said: “I am deeply saddened to hear of the tragic loss of a child’s life to knife crime in Hillingdon.
“This incident, that claimed the life of a 15-year-old boy, took place during this morning’s school run.
“A family has been devastated and the effects of this terrible incident will reverberate throughout our communities.
“As a parent of a teenage boy myself, I cannot imagine the pain the family is going through and I offer our full condolences and support.”
He said patrols would be stepped up in the area to reassure residents.
He added: “We work tirelessly with our borough Partners and communities to challenge violent crime and to stop the loss of young lives to knife crime.
“A homicide investigation will be launched following this morning’s tragic incident. Please work with us to prevent further young deaths by sharing what you know.”
Police said a post-mortem will take place but the boy has yet to be formally identified.
Local MP John McDonnell urged his constituents to come forward with any information on Twitter.
Anyone who witnessed this incident or has information is asked to call police on 101 or Tweet @MetCC quoting reference Cad 1681/11Jun.
To remains 100% anonymous contact the independent charity Crimestoppers on 0800 555 111.