Liam Williams and Josh Navidi are both doubts for Wales' warm-up match with France in Paris this weekend, before the autumn internationals.
Williams has only played one Test since the Rugby World Cup and could be released back to his region, Scarlets, for more game time in the Pro14. Navidi meanwhile is going through the concussion protocol after suffering a head injury in September in training with Cardiff Blues.
Wales assistant coach Neil Jenkins said of Williams: "We'll see how [Liam] goes. He probably does need game time, there's no doubting that. He played against England, that was his one game since the last Rugby World Cup last November, and he was pretty good that day.
"I see quite a few members of our squad who can play minimal or no rugby, but turn up and win a Test match. Liam would be in that category. He's a world-class player as far as I'm concerned. Whether he is involved on Saturday will be another thing."
The uncapped Bristol No 10 Callum Sheedy is yet to link up with the squad given the doubts surrounding whether Wasps or Bristol will face Exeter in this weekend's Gallagher Premiership final.
The Cardiff-born 24 year-old has impressed Jenkins, who won 87 caps himself at fly-half for Wales.
"Callum's played exceptionally well for Bristol to be fair to him, not just recently but over the past couple of seasons. He kicked very well in the final against Toulon," Jenkins noted. "Bristol play a little differently to how we play, he has heavy runners around him with Steven Luatua, Nathan Hughes and obviously Semi Radradra. I'd like to think that when he comes in with us he will have a bit of firepower around him in a different way. I'm looking forward to seeing him and meeting up with him."
Alun Wyn Jones is set to equal Richie McCaw's record of 148 Test caps if he plays against France, with Jenkins hailing the Wales captain's continued high standards late into his career. Jenkins said: "It's incredible really isn't it? To achieve what he has throughout his career in the position he plays in is incredible. He's in the front five, one of the hardest positions you can possibly play on a rugby pitch, yet he still seems like a young kid if you ask me.
"He turns up to training, is first to everything, very rarely gets beaten in anything if he does at all. That's the way he is. I've been lucky enough to be involved with him since the Wales Under-21s back in 2006 and from then up until now he is just world class, one of the best to ever play the game and is going to basically beat someone [McCaw] who is maybe the greatest player, who knows? It's an incredible achievement and whatever accolades come his way he definitely deserves that.
"I'd like to think he has a fair bit in him yet, but when the day does come and he is not wearing that jersey he will be sorely missed."