Lila, 19, stars in Calvin Klein's Fall 2022 campaign, which launched this week and celebrates the brand's latest underwear and loungewear collection.
In the campaign's images, the teenager is seen posing in several classic pieces, including a black tank top and jeans that show off the waistband of her CK logo underwear and another in a sheer black button-down layered top over a bra paired with black jeans.
The shoot is captioned: "A nod to the stripped-back images the brand is known for, capturing each talent's true confidence."
Lila joins the likes of actors Chloë Sevigny, Susan Sarandon and Dominic Fike in the campaign that was captured by British photographer Alasdair McLellan.
Lila took to Instagram to share the news of her new collaboration writing: “So grateful to be a part of the new @calvinklein campaign by @alasdairmclellan.”
Earlier this week, Moss, 48, who famously first modelled for Calvin Klein by posing topless in baggy jeans, told Vogue: “Fabien (Baron) said you should go and meet Calvin.
“So I went to the office and he booked me for this campaign CK Jeans.
“He wanted to put me under contract and that was a big thing, to be a model and have a contract.
“So funny, because Paul Cavaco said, 'Kate just take it, you're so short you're never going to work that much anyway.'”
Kate Moss has a long association with Calvin Klein, becoming the face of the label’s Obsession perfume campaign in 1993.
As one of the world's most successful models, she has helped her daughter achieve some of fashion's biggest milestones.
Lila will appear in the new Pirelli calendar that the supermodel first graced 28 years ago.
The aspiring model fronts Italian tyre manufacturer’s 2023 offering, named Love Letters to the Muse, alongside a string of top models including Karlie Kloss, Bella Hadid, Adut Akech, Emily Ratajkowski and Cara Delevingne.
Lila first started modelling at age 15 and made her catwalk debut at Miu Miu’s SS21 show.
She also appeared on her first Vogue cover earlier this year, and walked with her mother at Fendi’s show in Paris in 2021.
She recently told Vogue that her mother, who also began modelling at age 14, tried to dissuade her from starting a modelling career.
She said: “My mum always put me off [modelling]. She was always like, 'If you wanna do it, you can, but I wouldn’t recommend it.”