A hamstring injury forced the Englishman from the field during the 0-0 draw at Everton that marked the resumption of the Reds’ Premier League title push 10 days ago.
He missed out on the 4-0 win over Crystal Palace that effectively sealed the crown as a result, but is now closing in on a comeback.
Milner played a full part in training at Melwood on Tuesday afternoon and is expected to take his place in the squad in Manchester tomorrow.
The game has come too soon for Xherdan Shaqiri, who was also spotted in training this week having been absent since January.
The Swiss has been battling a muscle injury that was initially described as minor in recent months, but could be in line for minutes before the end of the campaign.
However, the same cannot be said for Joel Matip, the defender having revealed yesterday that he is out for the remainder of the season as a result of a foot injury.
He said: “This season I will be not back on the pitch but for next season, I hope I’m going to be quite early a direct help for the team.”
Jurgen Klopp has an otherwise fully fit squad to choose from and, with his players having gone eight days without a game, is likely to pick a similar line-up to that which dominated Palace at Anfield.
Predicted Liverpool XI vs Man City: Alisson, Alexander-Arnold, Gomez, Van Dijk, Robertson, Fabinho, Wijnaldum, Henderson, Salah, Firmino, Mane.