City have won the last four renewals of the competition to tie Liverpool’s all-time record of eight wins and are looking to become the first team to lift the cup five times in a row.
They face a Wycombe side who were relegated from the Championship last season but have made a strong start to the League One campaign.
Date, kick-off time and venue
Man City vs Wycombe is scheduled for a 7:45pm BST kick-off tonight - Tuesday, September 21, 2021.
The match will take place at Etihad Stadium.
Where to watch Man City vs Wycombe
The match will be not be televised live in the UK.
However, highlights will be available on Quest’s round-up programme from 10:30pm on Wednesday night.
Man City vs Wycombe team news
Pep Guardiola has confirmed that he will use a number of young players in tonight’s clash, with several of his first-team stars either out injured or just feeling their way back to fitness and needing to have their workloads managed.
“I don’t have any alternative… we are going to play a few young players,” Guardiola said.
“We have John (Stones), Aymeric (Laporte), Oleks (Zinchenko), Rodri and I think (Ilkay) Gundogan all of them injured.
“It’s a good opportunity for the academy - that’s why they are there.”
Predicted Man City lineup
Carson, Walker, Ake, Mbete, Wilson-Esbrand, Fernandinho, Palmer, Foden, Torres, Delap, Edozie
Man City vs Wycombe prediction
Guardiola has hinted at a weakened City side but we know all about the depth of his squad and just how seriously he takes this competition, given his incredible record in it.
Wycombe, it goes without saying, face a mammoth task.
Man City 4-0 Wycombe
Head to head (h2h) history and results
Man City wins: 2
Wycombe wins: 1
Betting odds and tips
Man City to win: 1/10
Wycombe to win: 19/1
Odds via Betfair (subject to change). Click here to find out more.