City's 2-0 win away to Stoke on Monday night sent Guardiola's men 16 points clear at the top of the Premier League table, with Manchester United sitting in second place and Tottenham back in third.
City have seven more games left to play this season, but need just two wins to claim the title.
Their next match is away to Everton on 31 March and, should City secure all three points at Goodison Park, the club can then be crowned champions at the Etihad Stadium the following week - against fierce rivals United.
A win in the Manchester derby, and one that would confirm the title in front of their own fans, would certainly be cause for some celebration for City but even if they cannot beat United, Guardiola's side can still do so in another iconic setting.
The club travel to take on Tottenham at Wembley on 14 April, a week after playing United, which could be the scene of City's title win should they fail to beat Jose Mourinho's side but do so against Spurs.
City could yet smash the Premier League points record for a single season, set by Chelsea in the 2004-05 campaign. The Blues, then managed by Jose Mourinho, finished the season on 95 points.
Amazingly, Guardiola’s side could theoretically achieve the feat by the end of April.