The Dutch full-back was sent off as Watford lost 1-0 in Saturday's Premier League clash, and has been hit with a three-match suspension.
Watford have appealed against the decision in a bid to have the 27-year-old available for Tuesday's league trip to Crystal Palace.
"I don't have doubts about the red card. It was very harsh, I can't say more," Silva told reporters at a press conference.
"It's better I just say it with these two words; for me it had a big influence on the match. At that moment the team were playing well - we were there to get a good result and compete. That moment had a big influence on the result.
"I saw two matches in the afternoon yesterday, the Liverpool and Manchester derbies, I saw more than one incident like the Zeegelaar one, and it was a yellow card every time.
"It needs to be equal for everyone - not making an example of one team.
"The Premier League is a tough league, don't make an example out of Watford.
"In the big matches, the big derbies, it's a tough game and a big game, you need to equal it with the others.
"Our game was two teams competing really hard but respecting each other. It was a fair game.
"The referee had a big influence and for me, it's not fair. We're appealing because we don't feel it is fair."
Additional reporting by the Press Association.