Spurs have yet to lose a game this season at their stadium, which they are due to leave at the end of the campaign. The plan is to play at Wembley next season before moving into their 61,000-seat stadium, a project costing about £800million, during 2018-19.
They face Everton on Sunday boasting a record of 11 wins and two draws in the Premier League. That form has been the foundation of another strong campaign, which has Spurs second in the table, 10 points behind leaders Chelsea.
Manager Pochettino said: “We are feeling that it is a very special season at White Hart Lane. It will be the last season there and we feel it is a very special moment whenever we play there.
“The energy is special, the fans are unbelievable. Every time we play there we take it as a special moment, and it is one of the keys of our good performances and results.”
Tottenham hope to have Toby Alderweireld, Jan Vertonghen and Harry Kane available for the meeting with Ronald Koeman’s team.
All three picked up knocks in the 4-0 win over Stoke last Sunday and of the trio, Alderweireld’s thigh injury is the cause for greatest concern.
Both Vertonghen and Kane are expected to be fit while Pochettino is also optimistic about Alderweireld.
Yet neither Danny Rose (knee) nor Erik Lamela (hip) has yet resumed full training and Spurs have put no date on when they will do so.