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Police have arrested a man on suspicion of murder, following the disappearance of a woman who has "not been seen for a significant period of time".
Diane Douglas, from Colton, near Norwich, was reported missing on 21 October by family members "who had lost contact with her for several years". Police have not said when, if it is known, she was last seen alive.
Relatives got in touch with Norfolk Constabulary after several unsuccessful attempts to get in touch with the 58-year-old, officers said.
On Saturday evening, police arrested a 56-year-old man in Wales on suspicion of murder. He was known to Ms Douglas, the force said in a statement, and was due to be taken to Norfolk for questioning.
The Norfolk and Suffolk Major Investigation Team said that after making a number of inquiries to trace Ms Douglas, to no avail, they had declared the case a so-called "no body" murder investigation.
Detective Inspector Matthew Connick said: "Although we hope to find Diane alive, we do believe it is highly likely that she has come to harm as she has not been seen for a significant period of time. We have therefore launched a murder investigation.
"A man has been arrested and will be questioned in due course on suspicion of her murder.
"We have a team of officers searching her last known address in Colton and we expect this search to continue for a number of days."
Anyone with information should contact Norfolk Police on 101 quoting Operation Entity.