Jack Klugman, who starred in TV's The Odd Couple and Quincy, M.E. has died at the age of 90.
His son Adam said he passed away on Monday afternoon in Los Angeles.
"He had a great life and he enjoyed every moment of it and he would encourage others to do the same," he said.
In the 1970s sitcom The Odd Couple, Klugman played sloppy sports writer Oscar to co-star Tony Randall's Felix, a fussy photographer.
In Quincy, M.E., which aired from 1976 to 1983, Klugman played an idealistic, tough-minded medical examiner.
He lost his voice to throat cancer in the 1980s but trained himself to speak again.
"The only really stupid thing I ever did in my life was to start smoking," he said in 1996.
He said of seeing people smoking in television and films: "It disgusts me, it makes me so angry. Kids are watching."
He returned to acting in a 1993 Broadway revival of Three Men On A Horse.
Klugman then split his time between TV, movies and the New York stage.