The Drag Race host will present the quick-paced wordplay game every Sunday for seven episodes with star-studded guests.
Celebrities go head-to-head in a vocabulary battle as they are challenged to fill in blanks and unmask missing words.
RuPaul said in a statement: “Now, more than ever before, people want to have fun, and Celebrity Lingo is here to serve it up generously.”
ITV have told press that the celebrities set to appear on the game show to “bank big money for charity” include Girls Aloud’s Kimberley Walsh, The Saturday’s Una Healy, Stacey Dooley and partner Kevin Clifton, Dr Ranj, and The Masked Singer presenter Joel Dommett.
The Drag Race connoisseur will also host the US version of the original show, Lingo, showing on CBS.
Celebrity Lingo begins on ITV on Sunday, September 4 at 6.30 pm.