For Sandra Oh, Grey's Anatomy was a game changer. The actress had been working for more than a decade — her credits included a TV movie based on the '80s police show Cagney and Lacey and a couple of episodes of the Ryan Murphy-produced series Popular — but it was her role as Dr. Cristina Yang that made Oh a household name. As soon as the show premiered in March 2005, in a favorable time slot following Desperate Housewives, Grey's was a hit. Behind-the-scenes controversies, such as former co-star Isaiah Washington's use of a homophobic slur about another one of her co-stars, T.R. Knight, and, later, Katherine Heigl's public complaints about "the material," meant the show was extra buzzy.
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