School closures and blanket social distancing measures 'increased coronavirus deaths'

PA
PA

Blanket social distancing measures and school closures during the coronavirus pandemic may have increased the overall death rate from the disease, researchers have said.

A new analysis revisited the piece of work by Professor Neil Ferguson and colleagues from Imperial College London which predicted that hundreds of thousands of deaths would occur if no action was taken to stop the spread of Covid-19.

The Imperial study, also known as Report 9, prompted the far-reaching social restrictions implemented in March – including the closure of schools for most pupils.

Now researchers from the University of Edinburgh have reassessed the model. The new study, published in the BMJ, examined and reproduced the main results in Report 9 using the information available at the time.

It specifically examined the effect of school closures – Report 9 found that closing schools reduced the reproduction number of Covid-19, but had the unexpected effect of increasing the number of deaths.

Researchers replicated these findings.

The authors wrote: "In the absence of an effective vaccine for Covid-19, school closures would result in more overall deaths than no school closures."

The study found that a number of "interventions" were highly effective at the peak of the pandemic, but then prolonged the epidemic and may have increased the number of deaths.

Researchers said the virus was able to spread faster to vulnerable people once lockdown restrictions were introduced than if some level of immunity had been allowed to build up in the young.

Social distancing was also a more effective tool at reducing deaths when only employed by people over 70, compared with among the general population, the University of Edinburgh said.

Graeme Ackland, professor of computer simulation from the University of Edinburgh’s School of Physics and Astronomy who led the study, said: "In the short-term, closing schools contributed to reducing the severity of the first wave, to the extent that Nightingale hospitals were not needed, but the decision has left us more vulnerable to subsequent waves of infection.

"Mitigating a Covid-19 epidemic requires very different strategies for different age groups and a different strategy from an influenza epidemic, with more focus on shielding elderly and vulnerable people."

Mr Ackland told the Telegraph: "Lockdown does mean that the number of deaths goes down, so there is a short-term gain, but it leads to long-term pain.

"If you had done nothing, it would all be over by now. It would have been absolutely horrendous but it would be over. It wouldn’t even have been completely lunatic to do nothing."

The researchers used a model called "CovidSim", which replicates simulations of the UK at a detailed level with 70 million simulated people replicating similar actions to those in the public – going home, to school, work, university and hospital.

Researchers used the model to examine various interventions, including social distancing of the over-70s, social distancing of the entire population, closure of schools and universities, and at-home isolation of people who develop symptoms – for seven days and 14 days.

They wrote: "The findings of this study suggest that prompt interventions were shown to be highly effective at reducing peak demand for intensive care unit (ICU) beds but also prolong the epidemic, in some cases resulting in more deaths long-term.

"This happens because Covid-19 related mortality is highly skewed towards older age groups.

"In the absence of an effective vaccination programme, none of the proposed mitigation strategies in the UK would reduce the predicted total number of deaths below 200,000."

They point out that when the interventions are lifted, there is still a large proportion of the population susceptible and a substantial number still infected.

"This then leads to a second wave of infections that can result in more deaths, but later," they wrote.

The authors said that the final death toll from Covid-19 depends largely on the age of those infected and not the overall number of cases.

They added that the modelling suggests that there needs to be some sort of prioritisation of aims in tackling the crisis – reducing the case numbers, reducing the death toll or reducing the burden on intensive care units.

Commenting on the study, Mark Woolhouse, professor of infectious disease epidemiology at the University of Edinburgh, said: "The headline result – that school closures in March could lead to a larger death toll over time – is intriguing and may cause some concern. In fact, this result applies to a specific, and probably unrealistic, scenario and should not be interpreted as a prediction.

"Nonetheless, this counterintuitive result does shed some light on the current debate about whether to allow herd immunity to build up in age groups that rarely experience severe consequences of infection.

"The key feature of the modelling exercise is that having flattened the first wave using social distancing measures ("lockdown"), the interventions are lifted and a large second wave results.

"In reality, measures are being reimposed in response to the second wave, so the scenario is unrealistic."

He added: "Though the modelled scenario may be unrealistic, it does illustrate the general principle that, of itself, lockdown solves an immediate crisis without providing a long-term solution. In trying to keep the epidemic suppressed, we risk a recurrent cycle of restrictions of one form or another.

"Rice et al also make the point that these results were available to policy makers when this model was first published on March 16th. The implication is that it was known then that school closures could have adverse impacts on the course of the epidemic beyond the first wave.

"Perhaps the key lesson that should be drawn from this study is the warning that if we allow short-term thinking to dictate our response to Covid-19 then we may not make the best decisions for minimising the public health burden over the longer term."

A spokesperson for Imperial’s Covid-19 Response Team, which produced Report 9, said the researchers have provided "independent confirmation that Imperial’s modelling in March was robust, reproducible and sound in its conclusions".

“We welcome this independent analysis of Report 9 as we continue to advance our understanding of the early epidemic," they said.

A Government spokesman said: "At every stage of our response we have been guided by the advice of experts and took decisive action from the outset to support the NHS and save lives.

"We have been doing everything we can to ensure the most vulnerable people in our society are protected.

"This includes testing all residents and staff in care homes, providing over 228 million items of PPE, ring-fencing over £1.1 billion to prevent infections in care homes and making a further £3.7 billion available to councils to address pressures caused by the pandemic."

Read more

Schools 'could be unsafe because so many teachers cannot get tests'

Pubs 'could close in days' as ministers thrash out lockdown plans-LIVE

'Worrying' number of patients in intensive care as Covid-19 cases rise

London sees more than 6,200 new coronavirus cases in a week

New restrictions 'set to hit England on Monday' as Covid cases surge

UK virus cases jump by 14,162 with death toll up by 70