So far, 49 cases of the new strain have been identified in Yorkshire and the Humber.
Public Health England said they are now looking into the spread of the mutation, which is currently a “variant under investigation”.
Residents have been told not to be “alarmed” at the spread of the latest strain, known as VUI-21MAY-01 or AV.1.
Greg Fell, director of public health in Sheffield, said his team had been observing the “triple mutant” variant and has found no reason to think it is more transmissible or resistant to vaccines.
Ministers have also insisted that they won’t “hesitate to put in measures that we think are necessary to try and tackle the transmission of any variants”.
Meanwhile, Germany has banned Britons from visiting the country after the country’s Public Health Institute designated the UK as a virus variant area of concern.
From midnight on Sunday, May 23, people travelling to Germany from Great Britain and Northern Ireland may only enter the country if they are a German citizen or resident.
Spouses and children under 18 of a German citizen or resident can also enter, as long as the household are travelling together.
Those with an urgent humanitarian reason such as an immediate family bereavement are also able to enter, however, anyone entering the country from the UK must quarantine for two weeks on arrival, even if they test negative for the coronavirus.
People who are only transferring from one flight to another will still be allowed in, however, they must remain in the airport transit area.
According to new figures, there are “early signs” of a potential rise in the proportion of people testing positive for coronavirus in England.
Office for National Statistics (ONS) figures, published on Friday, show that around one in 1,110 people in private households in England had Covid-19 in the week to May 15 – up from one in 1,340 the previous week.
The coronavirus reproduction number, or R value, in England has also risen slightly to between 0.9 to 1.1, up from between 0.8 and 1 last week, according to the latest Government figures.
It comes after the latest official figures showed that cases of the Indian variant of coronavirus in the UK have risen by more than 2,000 in the space of a week.
Despite the emergence of new variants, Boris Johnson has said he remains hopeful that England will be able to ease all remaining restrictions on June 21.
Speaking to reporters in Portsmouth, he said: “We will be letting everybody know exactly what sort of arrangements to expect for June 21.
“But what I can tell you, and just to stress that I am still seeing nothing in the data that leads me to think that we’re going to have to deviate from the roadmap - obviously we must remain cautious but I’m seeing nothing that makes me think we have to deviate.
“But on June 21 and vaccine certification — or Covid status certification I should say — people should bear in mind that I don’t see any prospect of certificates to go into pubs or anywhere else.”