Six people were hospitalised following a crash between a double-decker bus and a van on the A420 yesterday.
The van driver, the Stagecoach bus driver and 12 passengers all received injuries in the crash near Great Coxwell between Faringdon and Grea Coxwell around 10.15am yesterday.
Police officers, the ambulance service and the fire service all rushed to the scene and the road was closed for several hours.
The van driver, 40s, suffered serious but not life-threatening injuries and he was taken to the John Radcliffe Hospital in Oxford for treatment.
He remains in a stable condition.
The bus driver, a man in his 60s, and four of the 12 passengers went to Great Western Hospital for treatment after sustaining minor injuries.
The other eight passengers did not require hospital treatment.
The van was a white Mercedes-Benz Sprinter.
Investigating officer PC Tim Cameron, of the Joint Operations Unit for Roads Policing said: “I am appealing for witnesses to this incident whereby a driver has sustained serious injuries.
“I would ask that anyone who was in or near the area where the collision happened to get in touch with us if you saw anything or have any information on it.
“Also, I would urge any motorists in the area that have a dash-cam to please check their recordings in case anything significant was caught as it could help our investigation, and then send it to us.
“You can contact us by calling the 24-hour non-emergency number 101 or by making a report on our website, quoting reference number 43220413491.”
It comes less than a month after three young men died in a crash on the A420 near Faringdon.
Lawrence Bruce, 20, Joseph Shape, 18, and Calum Leighton, 18, were in a black Ford Fiesta heading towards Oxford when the car was involved in a collision with a coach and a white Alfa Romeo near Faringdon on August 21.