- Oops!Something went wrong.Please try again later.
Silent Witness is celebrating its 25th anniversary series with a "clash of the titans" that sees the show's original and current stars jostle for position in the post mortem room.
David Caves who plays Jack Hodgson in the BBC One long-running forensics drama said: "It's a clash of the titans between Nikki and Sam."
Fox, who took the reins as chief pathologist after Burton's exit, said it was "nerve-racking" working alongside the woman who made the show's success.
She said: "They tread carefully around each other. At one point in the first episode, Sam intervenes during a post-mortem that Nikki is doing. Nikki is trying to get the measure of Sam and fathom her out."
Asked what it was like acting a post-mortem examination scene in front of Burton, Fox admitted: "Nerve-racking! She is the empress of the post-mortem, so the pressure was on. I made sure I was very, very well prepared.
"The post-mortems tax my brain, and I'm always delighted to get through them. But this time I had Sam interrupting all the time. That creates great character moments."
Burton said she had loved the opportunity to work alongside Fox: "It was wonderful. Coming together with Emilia, who's held this show together so brilliantly for so many years, was lovely. It was extraordinarily special.
"To see these two powerful characters working together was amazing. In the script, they call them the two titans of the medical world."
The actor added that she had enjoyed stepping back into her old role and was pleased to see that her trailblazing character had not disappeared into obscurity.
She said: "I loved the fact that she was still very much pioneering and busy and connected – that meant a lot to me.
"I was very, very happy that she wasn't being tracked down to some sort of remote corner of a British village where she was judging hen competitions!"
Silent Witness begins on Monday at 9pm on BBC One.
Watch: Good Housekeeping has tea with Emilia Fox