The Reds stunned the Emirates in August, scoring four goals in 18 minutes on their way to a 4-3 win over Arsenal.
It would set the tone for an exceptional start to the season but Jurgen Klopp’s side have won just two of 12 matches in 2017, a run of form that has seen them exit both domestic cup competitions and slip from second in the table to fifth.
Goalkeeper Mignolet insists his side can have no excuses for their decline in form but is confident their recent struggles will be put to one side for the visit of their top four rivals.
"There will be a few things we could say: we could say we had a few injuries, we've had a lot of games, Sadio (Mane) went to the African Nations Cup - but in the end that'd all be about excuses and we don't want to look for them. It's about looking forward," Mignolet told the club website.
"We know January wasn't really the best of months but we don't want to look back.
"We have an opportunity again against Arsenal and that's where we have to look forward.
"We showed at the Emirates at the beginning of the season that we can get a result, play really good football and create chances against Arsenal.
"That's what we have to look to do again. It's the next game that counts and that's why we're looking forward.
"You can use (criticism) as some sort of energy to get yourselves back up again and push yourselves even further and harder, looking forward to the next opportunity. That's what we have to do.
"It's a new game, a new 90 minutes to play and this weekend it'll be the only thing that matters."