Stand Up To Cancer is back for its annual Channel 4 fundraiser, including a long list of celebrities willing to throw their weight behind the campaign.
Friday night also sees two scary series begin streaming in time for Halloween - the third season of You at Netflix, and a TV spin-off of I Know What You Did Last Summer at Amazon.
Strictly Come Dancing is back on the dancefloor on Saturday night with a few notable exceptions, and Sally Lindsay launches frothy new sleuthing series The Madame Blanc Mysteries at Channel 5.
On Sunday night, cosy drama returns with ITV's The Larkins, while million-pound prizes are handed out to planet-saving campaigns in The Earthshot Prize on BBC One.
Stand Up To Cancer - Channel 4 - 7.30pm
Annual fundraiser Stand Up To Cancer takes over at Channel 4 tonight with Davina McCall, Maya Jama, Alan Carr and Adam Hills hosting proceedings.
It's jam-packed with celebrity cameos, including Olivia Colman, Jack Black, Harry Styles, David Oyelowo, Kim Kardashian and Usain Bolt to name just a few.
Look out for the ever-popular Celebrity Gogglebox, too, set to be a highlight of the evening.
You - Netflix
The darkly comic serial killer series returns for a third time, now with the fresh twist that Joe's (Penn Badgley) wife Love (Victoria Pedretti) is just as unhinged as he is.
Now living in the San Francisco suburbs as new parents to a baby boy, the couple are unable to shrug off their murderous impulses as they find new enemies amongst their rich neighbours.
I Know What You Did Last Summer - Amazon Prime Video
Nineties horror classic I Know What You Did Last Summer gets a TV series spin-off just in time for Halloween.
Like the films before it, the series starts with the premise that a group of friends are being hunted by a serial killer for a crime they covered up a year earlier.
Strictly Come Dancing - BBC One - 7pm
We're back in the ballroom on Saturday night, but not all of the couples are joining us.
Still, the live show promises plenty of excitement as top scorers John Whaite and Johannes Radebe return as well as Rhys Stephenson and Nancy Xu who'll be hoping to win another 10.
The Madame Blanc Mysteries - Channel 5 - 9pm
Sally Lindsay stars in this entertaining detective series which she also wrote.
Her character is an antiques dealer who travels to the south of France to find out how her shady husband died, and why he had pawned off all of their assets.
The amateur sleuthing series also includes appearances from Sue Holderness and Sue Vincent.
The Larkins - ITV - 8pm
The Darling Buds of May reboot continues tonight, starring Joanna Scanlan and Bradley Walsh as Ma and Pop Larkin.
Sabrina Barlett takes on the role of Mariette that made Catherine Zeta Jones famous and in this episode she takes centre stage with a love dilemma over Charley the taxman, or the charming Tom Fisher.
The Earthshot Prize: Repairing Our Planet - BBC One - 8pm
If you're not familiar with The Earthshot Prize, Prince William and Sir David Attenborough have teamed up to fund inspiring projects aiming to repair the planet by awarding five £1 million prizes each year over the next 10 years.
The episodes in this series so far have explored the ideas up for consideration and tonight, Dermot O'Leary and Clara Amfo present the first awards ceremony from Alexandra Palace, with performances from Coldplay, Yemi Alade, KSI, Shawn Mendes and Ed Sheeran.
Watch: Who's judging this year's Strictly?