Study reveals fewer mammograms may be safer for breast cancer survivors over 50

-Credit: (Image: Reach Publishing Services Limited)
-Credit: (Image: Reach Publishing Services Limited)


A national trial that looks at the frequency of follow-up mammograms for those aged 50 years and over who’ve had breast cancer has recently finished, with over 70 Somerset patients contributing to the study.

After a person finishes treatment for breast cancer, they have a treatment summary consultation, followed by regular mammograms to check that the cancer hasn’t come back, and open access to Somerset NHS Foundation Trust’s breast care clinic.

Guidelines recommend that a person should have mammograms every year after treatment for breast cancer, but doctors aren’t sure how often they should have them or how long for.

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Yearly mammograms can cause anxiety in some people, and research already carried out suggests that those over 50 may be able to have fewer mammograms if they are supported in other ways.

Kerry Rennie, a senior research nurse at Somerset NHS Foundation Trust, explained: “Over ten years ago, the MAMMO-50 clinical research study was set up to look at whether we could safely reduce the frequency of mammograms from annually to every three years in those over 50.

“This study involves looking at the frequency of mammograms for women with early breast cancer to find an optimum time, as this has never been standardised across the UK.”

Miss Caroline Osborne, a consultant breast surgeon at the trust and principal investigator for the study at Yeovil Hospital, added: “During the trial, we found that the follow-up protocol for many hospitals in the country was different.

“We initially set up the study at Yeovil Hospital, and recruited our first patient in June 2014, with Kerry and Mr Ansari, the original principal investigator, leading. Consultant breast surgeon Miss Amanda Thorne and our mammography clinical nurse specialist, Lisa Gale, were also involved at Musgrove Park Hospital.

“This means that our very first patient has been followed up within the study for ten years, and during that time, we’ve recruited an impressive total of 38 patients at Yeovil Hospital and 33 at Musgrove Park Hospital.

“We want to thank all those patients who decided to go into a study like this, which has unknown outcomes.

“They’ve put their trust in us to go into a study, with all the additional follow-up that comes with it, too – with lots of phone calls and discussions over the years.

“When I see those patients in the clinic, they always tell me how they’re pleased to be involved with medical research, and in this particular study, a lot of patients were also happy that they didn’t need to have so many mammograms.”

The Musgrove Park Hospital team is pictured (left to right): Miss Amanda Thorne - consultant oncoplastic breast surgeon, Lisa Gale - clinical nurse specialist for mammography.
The Musgrove Park Hospital team is pictured (left to right): Miss Amanda Thorne - consultant oncoplastic breast surgeon, Lisa Gale - clinical nurse specialist for mammography.

Many patients who come in for a mammogram are understandably anxious about the result, and some also prefer less frequent hospital visits.

Zenaida Dagutao, a clinical research assistant practitioner at Somerset NHS Foundation Trust, said: “While everyone is different, we generally find that patients are highly anxious before their follow-up appointment as they have their mammogram and then need to wait for the result, which can sometimes take a little while.

“By saying to them that they don’t need to come in for a mammogram so frequently, it can help with their anxiety in many ways, so they don’t have that fear leading up to each investigation.

“Another practical benefit for patients who do not come in for as many scans is reduced radiation exposure.”

Miss Osborne added: “We now have the interim results of the study, which suggest that there’s no difference in outcomes for patients whether they have a three-yearly or annual mammogram appointment, although this will need to be officially ratified by the central study team.

“The final results will only be available once every patient in the UK who entered it has finished the follow-up, but these early findings are encouraging.

“This research study has been a real team effort, and our breast care radiographers are vital in helping us collect data.

“There’s a lot of tracking involved in this study, with Zenaida, Kerrie and our clinical research, breast surgeons, clinical nurse specialists, and radiology teams working tirelessly to track the mammograms that patients taking part were having over the years.

“Once the study has officially completed, it’s likely that national guidance could change, although we’d need to be careful not to pre-empt this ahead of the outcomes. We would, of course, change our practice in line with these guidelines.”