Immigration minister Robert Jenrick has dismissed previous Tory targets to limit legal net migration to the tens of thousands.
The PM has confirmed a shake-up of his top team, including some high-profile sackings and a promotion for Liz Truss.
Communities secretary Robert Jenrick criticised Brussels as a row continues over sausages and chicken nuggets.
It comes amid the row over Richard Desmond’s £1bn, 1,500-home scheme in east London.
The ability to tighten restrictions in individual regions will be part of the NHS test, track and trace system.
The government wants Reception, Year 1 and Year 6 pupils to start returning in smaller class sizes from 1 June at the earliest.
The scientist stepped down from his role on Sage but a minister twice accused of breaching lockdown rules remains in his job.
Housing Secretary Robert Jenrick is accused of breaking lockdown rules twice - by travelling to his second home in Herefordshire and also visiting his elderly parents.