Police are believed to have discovered a 'relevant clue' according to Portuguese media reports.
Police are searching a reservoir close to the hotel where the young girl disappeared in 2007.
A small number of children have, like Madeleine McCann, been missing for more than 10 years, with investigations into their disappearances often ongoing decades later.
Police investigating the disappearance of Madeleine McCann 16 years ago have begun a search of a reservoir in Portugal.
Portuguese police have formally identified German national Christian B as a murder suspect.
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German investigators have begun searching a plot of land near Hanover in northern Germany.
Authorities in Germany said last month they had identified a 43-year-old German citizen as a suspect in the case.
The UK police force investigating the disappearance of Madeleine McCann has denied a letter sent to her parents revealed evidence of her death.
Kate and Gerry McCann said suggestions they had received a letter from German prosecutors about their daughter's death were 'false'.
The 43-year-old suspect in Madeleine's disappearance is currently in a German prison.
German authorities said they have 'some evidence' that Madeleine McCann is dead.
Jim Gamble said the McCann case is “pretty unique”.
It is one of seven lines of inquiry that authorities have asked for help with.
Authorities in Germany believe Madeleine, who has been missing for 13 years, has died.
Kate and Gerry McCann have always vowed to continue searching for their daughter since her disappearance in Portugal 13 years ago.
A 43-year-old German national has been identified as the prime suspect in the toddler's disappearance.
Some £12m has been spent so far in searching for Madeleine, who went missing in Portugal in 2007
Kate and Gerry McCann were at a restaurant in Scotland when they were photographed, it was reported.
Goncalo Amaral was removed from the case after criticising British police.
The police investigation into Madeleine McCann's disappearance has cost almost £12 million.
Kate and Gerry McCann refused to take part in the documentary.
‘Find Madeleine - Leaving No Stone Unturned’, now has more than £800,000 in assets.