Alderweireld played 90 minutes versus Newport on Wednesday, his first appearance since tearing his hamstring against Real Madrid 14 weeks ago.
And the Belgium international has declared himself ready to face Arsenal after returning from the longest lay-off of his career.
Starting Alderweireld against Arsenal would not be without risk, particularly given Arsene Wenger's side now have the razor-sharp Aubameyang in their ranks.
Alderweireld has already faced Aubameyang when Tottenham beat Borussia Dortmund 3-1 in September, and while the striker drew a blank that day, he scored in both of Dortmund's Europa League wins over Spurs in 2016, games the Belgium international also played in.
"He's very quick, he's a good finisher, he has it all," Alderweireld said.
"He is in a good moment now as well so it's going to be very difficult to beat him but I think we will be ready for it.
"You have to work your mind. One against one, on the same line, he will beat you, so you have to be very clever, you have to read the situation and try to beat him with your head."