Reports on Saturday night suggested the match was set to be postponed due to positive tests among Palace staff after a number of players also tested positive.
Palace put a late request in to the Premier League to postpone the game but both clubs have confirmed the match is on.
Tottenham’s recent 2-2 draw against Liverpool, where Harry Kane scored just his second league goal of the season, will have given them plenty of confidence, as will their win over West Ham in midweek to take them into the last four of the Carabao Cup.
While Spurs are seventh in the table, six points behind Arsenal in fourth, they have played three matches fewer than the Gunners and so they are in a strong position to move towards the top four when they catch up with the fixture backlog.
The Eagles have won once away from home all season, though that was against Man City, and they will have to be at their best to stop a Tottenham side that are building momentum.
Date, kick-off time and venue
Tottenham vs Crystal Palace is scheduled for an 3pm GMT kick-off on Sunday, December 26, 2021.
It will take place at the Tottenham Hotspur Stadium.
Where to watch Tottenham vs Crystal Palace
TV channel: The game will be broadcast on BT Sport 1, with coverage starting at 2:30am GMT ahead of kick-off an hour later.
Live stream: BT Sport subscribers will be able to watch the game through the website or BT Sport App.
Tottenham vs Crystal Palace lineups and team news
Tottenham starting XI: Lloris, Sanchez, Dier, Tanganga, Emerson, Hojbjerg, Skipp, Reguilon, Lucas Moura, Son, Kane
Subs: Doherty, Winks, Gil, Rodon, Alli, Gollini, Bergwijn, Ndombele, Davies
Crystal Palace starting XI: Butland, Ward, Andersen, Tomkins, Mitchell, Gallagher, Kouyate, Hughes, Ayew, Edouard, Zaha
Subs: Guehi, Mateta, Schlupp, Matthews, Kelly, Ferguson, Riedewald
Tottenham vs Crystal Palace prediction
Spurs seem to be finding some real form under Conte now, while Palace are not quite producing their best performances as often as they were at the start of the season.
The Tottenham defence is not yet as tight as their manager would like, but the likes of Kane and Son will cause the visitors plenty of problems. Palace have not kept a clean sheet since the start of November, and that run looks unlikely to end here.
Tottenham to win, 3-1.
Head to head (h2h) history and results
Tottenham wins: 32
Crystal Palace wins: 13