Having been knocked out of the Europa Conference League this week after forfeiting their final group game, Spurs know that this competition may well represent their best chance of ending their long trophy drought.
West Ham, meanwhile, have enjoyed a terrific run in this year’s competition so far, beating both Manchester City and Manchester United, though their league form has dropped off in recent weeks.
Date, kick-off time and venue
Tottenham vs West Ham is scheduled for a 7:45pm GMT kick-off on Wednesday, December 20 2021.
The game will be played at the Tottenham Hotspur Stadium.
Where to watch Tottenham vs West Ham
TV channel: The match will be televised on Sky Sports Football and Main Event.
Live stream: Sky Sports subscribers will be able to watch the match online via the website or Sky Go app.
Tottenham vs West Ham team news
Tottenham XI: Lloris; Sanchez, Dier, Davies; Doherty, Skipp, Hojbjerg, Reguilon; Bergwijn, Lucas, Kane.
Subs: Gollini, Royal, Rodon, Tanganga, Winks, Lo Celso, Ndombele, Dele, Son.
West Ham XI: Areola; Johnson, Ashby, Dawson, Diop, Masuaku; Rice, Soucek; Vlasic, Lanzini; Bowen.
Subs: Randolph, Baptiste, Alese, Fredericks, Kral, Noble, Fornals, Benrahma, Yarmolenko.
Tottenham vs West Ham prediction
This looks a difficult game to call - West Ham’s run in this competition has had a feeling of destiny about it, but Tottenham are coming off what may well be looked back on as a landmark result under Antonio Conte in their draw with Liverpool.
Tottenham to win on penalties.
Head to head (h2h) history and results
Tottenham wins: 98
West Ham wins: 66