Giving evidence to MPs today on the handling of the Covid pandemic, Matt Hancock announced an “outbreak” of the rare virus.
The Health Secretary described the situation as “absolutely standard” - and said he dealt with “these sorts of outbreaks all the time.”
A spokesman for Public Health Wales said the index case was acquired overseas and the two patients are members of the same household.
Richard Firth, consultant in health protection at Public Health Wales, said: “Confirmed cases of monkeypox are a rare event in the UK, and the risk to the general public is very low.
“We have worked with multi agency colleagues, following tried and tested protocols and procedures, and identified all close contacts.
“Actions have been put in place to minimise the likelihood of further infection.
“Monkeypox is a rare disease caused by the monkeypox virus and has been reported mainly in central and West African countries.
“Monkeypox, in most cases, is a mild condition which will resolve on its own and have no long-term effects on a person’s health. Most people recover within a few weeks.”
Monkeypox is a rare disease that is caused by infection with monkeypox virus.
Monkeypox was first discovered in 1958 during an outbreak of pox-like disease in monkeys.
The first human case was recorded in 1970 in the Democratic Republic of Congo and since then the infection has been reported in a number of central and western African countries.
The symptoms include fever, headache, muscle aches, backache, swollen lymph nodes, chills and exhaustion.
Within 1 to 5 days after getting a fever, a rash develops, often beginning on the face and then spreading to other parts of the body, such as the hands and soles of the feet.
The rash will finally form a scab before falling off.
Monkeypox is not deadly - it is a mild condition which will often resolve on its own and has no known long-term effects on a person’s health.