Cops arrived at the scene around 11.30am this morning, following reports of the incident.
In pictures provided to the Glasgow Times, multiple police cars can be seen, as well as officers managing the traffic.
An eyewitness also said that the road has been partially closed.
A force spokesperson has confirmed that recovery has been arranged.
A Police Scotland spokesperson said: “Around 11.30am on Thursday, September 22, police were called to Castle Street, Glasgow, following a report of a two-vehicle crash.
"Recovery has been arranged.”