A total of 15,329,617 people have now had a second dose of a coronavirus vaccine, while 34,505,380 have had one dose.
On Saturday, just seven Covid deaths were reported and 1,907 new cases.
Despite tumbling cases and deaths, Foreign Secretary Dominic Raab has said that social distancing and masks may still be required after June 21.
Prime Minister Boris Johnson thanked those who had made the vaccination rollout possible as the UK reached the milestone of 15 million fully vaccinated people.
He tweeted: “15 million people across our United Kingdom have received two doses of a COVID vaccine. Thank you to everyone who has made this possible. Please keep coming forward to get your jabs to give yourself maximum protection from the virus.”
NHS chief executive Sir Simon Stevens said: “The biggest vaccination programme in NHS history continues to break records thanks to careful planning and, just as we promised, April has seen a focus on second doses with over 15 million people now benefiting from the maximum immunity offered by the vaccines.
“It is vital that when it is your time everybody gets their second dose for stronger and longer lasting protection.”
Government data up to May 1 shows that of the 49,834,997 jabs given in the UK so far, 34,505,380 were first doses – a rise of 143,175 on the previous day.
Some 15,329,617 were second doses, an increase of 372,304.
NHS England data shows a total of 5,138,786 jabs were given to people in London between December 8 and May 1, including 3,611,726 first doses and 1,527,060 second doses.
This compares with 5,550,858 first doses and 2,379,828 second doses given to people in the Midlands, a total of 7,930,686.