Police told KSL.com that the suspect, a 21-year-old woman, was taken into custody on Saturday and booked into the Salt Lake County following the threat.
The woman allegedly "posted threats of violence" on Yik Yak, a social message app where users are anonymous, ahead of the Utah Utes game against the San Diego Saint Aztecs of San Diego State University, reports said.
"If the football team did not win the game, (she) was going to detonate the nuclear reactor that is located in the University of Utah causing a mass destruction," a police affidavit obtained by Yahoo Sports said.
Police noted that the student was "aware of where the reactor is located and attends class in the same building where the reactor is housed”, but did not name the invidiual. An investigation is thought to be ongoing.
The arrest comes after a 19-year-old University of Utah student was arrested for making a similar threat on the same social media app, Yahoo Sports reported.
The Utah Utes beat their San Diego opponents on Saturday 35-7.