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The first-team coach and former long-serving midfielder was temporarily handed the first-team reins at Old Trafford on Sunday when Solskjaer was finally relieved of his duties following a humiliating 4-1 loss at Watford - United’s fifth defeat in seven Premier League outings.
Carrick will oversee affairs while the club look for an interim boss until the end of the season before moving for a long-term target next summer.
The ex-England international will be desperate to see a reaction from United’s players for what is a key fixture in eastern Spain.
United currently sit top of Group F with two matches left to play, though are level on points with Unai Emery’s Villarreal and in front only on head-to-head, with Atalanta only two points further back as they travel to face Young Boys in Switzerland.
Date, kick-off time and venue
Villarreal vs Manchester United is scheduled for a 5:45pm GMT kick-off today - Tuesday, November 23, 2021.
The match will take place at the Estadio de la Ceramica - better known as El Madrigal - in Villarreal, Spain.
Where to watch Man United vs Villarreal
TV channel: This evening’s match will be televised live on BT Sport 3, with coverage beginning at 5pm.
Live stream: BT Sport subscribers will also be able to watch the action unfold online via the website or BT Sport app.
Villarreal vs Man United team news
United defender Raphael Varane remains sidelined for a number of weeks with a hamstring injury, though captain Harry Maguire is available for European competition amid a one-match domestic suspension for his two yellow cards - which came in the space of just seven minutes - in the Watford debacle.
Paul Pogba is also out for up to three months with a thigh injury suffered with France, while Mason Greenwood is isolating after testing positive for Covid-19.
Luke Shaw is out with a head injury suffered against Watford, while Edinson Cavani is still dealing with a tendon issue.
Villarreal XI: Villarreal: Rulli; Foyth, Albiol, Torres, Estupinan; Capoue, Trigueros, Parejo Moi Gomez; Pino, Danjuma.
Subs: Sergio Asenjo, Mario, Alcacer, Iborra, Chukwueze, Dia, Raba, Moreno, Pena, Mandi, Pedraza, Iker.
Man United XI: De Gea; Wan-Bissaka, Lindelof, Maguire, Telles; McTominay, Fred; Sancho, Van de Beek, Martial; Ronaldo.
Subs: Heaton, Henderson, Bailly, Dalot, Fernandes, Lingard, Mata, Matic, Amad, Rashford.
Villarreal vs Man United prediction
As bad as United have been under Solskjaer over recent months, Saturday at Watford was truly a new low.
David de Gea’s frankly astonishing post-match claim that the team “don’t know what to do with the ball” or “know how to defend properly” painted a dismal picture of the state of a rudderless, hopelessly under-coached squad stuck in a massive rut.
While it had been evident for some time that Solskjaer was well out of his depth, United’s players must start taking responsibility for some of their wretched displays.
Carrick will have his own ideas about the improvements that need to be made, having had a front-row seat to the recent disasters in his role as first-team coach.
We expect a reaction of sorts, but not enough to topple a Villarreal side on a three-match unbeaten run, with former Arsenal boss Emery reaffirming his commitment to the club after links with Newcastle.
Another entertaining draw between these two teams could beckon, with Cristiano Ronaldo no doubt keen to play the role of hero again.
Villarreal 2-2 Manchester United.
Head to head (h2h) history and results
Man United wins: 1
Villarreal wins: 1