Parts of the UK could see winds of up to 70mph and up to 40mm of rain during the weekend.
The Met Office has issued yellow weather warnings for the east and south of England and for the north east of Scotland over Aberdeenshire, Orkney, and Shetland.
A Met Office spokesperson said: "60-70mph gusts would be enough to cause some problems, delays to transport, some short loss of power possible, could be some spray on the coasts.
"Certainly for north east Scotland the winds are stronger, there's more chance there of some branches coming off trees, if people have things out in the garden then bits will be blown around, but not quite enough to cause real structural damage.
"It's mainly transport disruption.
"In north east Scotland flooding of some homes and buildings is possible and flooding of some roads and flooding in the odd bit of property as well across the Southeast."
Strong winds and heavy rain are expected for some coastal areas on Saturday, including in East Anglia, Essex, Kent, and the south coast over the Isle of Wight and Lyme Regis from 1pm until 10pm.
Ramsgate in Kent is expected to see gusts of up to 56mph, with 52mph on the Isle of Wight.
There could be delays to road, rail, air and ferry services, as well as for high-sided vehicles crossing exposed routes and bridges.
The Met Office has also warned of power cuts.
Orkney and Shetland can expect heavy rain from 4pm on Saturday until 6am on Sunday, with flooding and transport disruption possible.
Strong winds are forecast for north Aberdeenshire and as far as Orkney and Shetland from midnight on Saturday until 3pm on Sunday.
Wet and windy weather could continue into the new week, particularly in England and Wales on Monday night and Tuesday morning, the Met Office said.