West Ham will face London rivals Chelsea without star man Marko Arnautovic after the Austrian lost his battle to overcome a knee injury in time for Sunday’s clash.
The top scorer, who won three individual awards following his maiden term in east London last season, picked up a knee problem against Arsenal last month which flared up and forced him off after scoring in the win over Everton last weekend.
Arnautovic aside, manager Manuel Pellegrini sticks with the same side which brought him his first points of the Premier League season at Goodison Park last weekend, which Michail Antonio coming in as the only change as summer signing Lucas Perez awaits his first start of the season.
On Antonio, Pellegrini told Standard Sport this week: "He is a very useful player, because he is very fast and the way he played in the last minute when Marko couldn’t continue is the way he must play every game.
"Maybe it is not only his confidence. He needs to work the whole week completely because he couldn't do it for a long time. Now, he is working well and working that way he will recover."
Andy Carroll, Manuel Lanzini and Winston Reid remain long-term absentees while Jack Wilshere misses out after undergoing surgery.
Meanwhile, Eden Hazard returns for Chelsea as Maurizio Sarri's men aim to continue their perfect start to the Premier League campaign.
Hazard was left in London as the Blues travelled to Greece for Thursday's 1-0 win over Europa League group rivals PAOK, but the Belgium international is back in the side for the trip to London Stadium.
Mauarizio Sarri makes just one change to the side which beat Cardiff 4-1 last Saturday, with Europa League match-winner Willian replacing the injured Pedro.
West Ham: Fabianski, Zabaleta, Diop, Balbuena, Masuaku, Rice, Yarmolenko, Obiang, Noble, Felipe Anderson, Antonio.
Subs: Cresswell, Snodgrass, Adrian, Sanchez, Ogbonna, Fredericks, Lucas Perez
Chelsea: Kepa, Azpilicueta, Rudiger, Luiz, Alonso, Kante, Jorginho, Kovacic, Willian, Giroud, Hazard
Subs: Fabregas, Barkley, Caballero, Moses, Zappacosta, Cahill, Morata