A Wrinkle in Time trailer: Behold the power of Oprah in Ava DuVernay's Disney adaptation

Oprah Winfrey, Mindy Kaling, and Reese Witherspoon.

That's a trio you don't want to mess with. They star as Mrs. Which, Mrs. Who, and Mrs. Whatsit respectively: three mysterious women who aid a young girl, Meg Murry (Storm Reid), in the search for her missing scientist father.

Disney's new film adapts Madeleine L'Engle's 1936 novel of the same name, with a first trailer lavishly unveiled at this year's D23 convention.

What's most exciting, however, is the talent behind the camera on this one. A Wrinkle in Time marks Ava DuVernay's grand return to feature film after Selma, having since created TV's Queen Sugar and directed and written the Oscar-nominated doc 13th.

The film also stars Gugu Mbatha-Raw as Meg's mother, alongside Zach Galifianakis, Levi Miller, Michael Peña, and André Holland.

A Wrinkle in Time hits UK cinemas 23 March 2018.