Amy Schumer credits online abuse for diagnosis of rare disease

Schumer was diagnosed with Cushing's syndrome after her appearance on The Tonight Show with Jimmy Fallon
Amy Schumer was diagnosed with Cushing's syndrome after her appearance on The Tonight Show with Jimmy Fallon - NIPI

Amy Schumer has credited online abuse for leading to her diagnosis of a rare hormonal disorder known as Cushing’s syndrome.

The US comedian was mocked for her “puffier” face by internet trolls when she appeared on a chat show this month, but said the comments drove her to seek medical advice.

Schumer, 42, initially put the change in her appearance down to her endometriosis, a painful gynaecological condition.

“I’ve enjoyed feedback and deliberation about my appearance as all women do for almost 20 years,” she said. “There are some medical and hormonal things going on in my world right now but I’m okay.”

However, the Trainwreck actress has now revealed she had been diagnosed with Cushing’s syndrome, which had been caused by “getting steroid injections in high doses”.

The disorder can result in symptoms including a round face, weight gain, muscular weakness, depression and high blood pressure, according to the NHS.

‘Crazy couple of weeks’

Interviewed by the News Not Noise newsletter, Schumer said her family had been through a “crazy couple of weeks” as she underwent a series of medical tests while promoting her comedy series Life and Beth.

She said she had been in “MRI machines four hours at a time, having my veins shut down from the amount of blood drawn and thinking I may not be around to see my son grow up”.

“So finding out I have the kind of Cushing that will just work itself out and I’m healthy was the greatest news imaginable,” Schumer added.

Cushing’s syndrome is usually a result of taking steroid medicine, but can also be caused by excessive levels of the stress hormone cortisol or a tumour.

“I feel reborn… this is a good example of the fact that we never know what is going on with someone,” Schumer said.

“Everyone is struggling with something. Maybe we can all be a little kinder to each other and ourselves.”

Schumer has frequently been candid about her health issues, saying she “felt like a new person” in 2021 after having her uterus and appendix removed to treat her endometriosis.

She also suffered hyperemesis gravidarum, an extreme form of morning sickness, when she was pregnant with her son, Gene.