Comedian and children's author Walliams will star in an adaptation of his 2021 book of the same name for BBC One, nearly a decade after his first Gangsta Granny book was made into a TV film.
But while Walliams reprises his character as dad Mike, the rest of the cast has had an overhaul – with Cilla star Smith taking on the role of his wife, mum Linda.
In the first image released from the set, Walliams and Smith are shown with deep fake tans, heavily styled blonde hair, and glamorous outfits as the competitive dancing fans disappointed that their son Ben does not share their passion for ballroom.
The picture also includes new casting Archie Yates (Home Sweet Home Alone), who plays main character Ben.
In the 2013 BBC adaptation of Gangsta Granny, Walliams was joined by Miranda Hart as Linda, Reece Buttery as Ben, and Julia McKenzie as Granny.
Rob Brydon played Mr Parker and Robbie Williams was Linda's favourite dancer, Flavio Flavoli, from a Strictly Come Dancing-inspired TV show.
In the sequel, Mr Parker will be played by Griff Rhys Jones and Flavio by Kevin Bishop.
The Queen in the original story was played by Joanna Lumley, but the part will be taken over by Maggie Steed in the sequel.
At the end of Gangsta Granny, Ben's beloved Granny (aka The Black Cat) died after an escapade with the Crown Jewels.
But a year on, with a new spate of thefts occurring, all signs point to The Black Cat again - surely it's impossible that she could be behind the plot?
Walliams said: “It is a thrill to revisit these characters in a brand new story. I hope families are going to love this comedy adventure story. A huge thank you to the BBC for making it happen.”
Watch: David Walliams impersonates Billie Eilish on Comic Relief